Chicago River at Night, photograph by Daniel Schwen

A River of News Will Flow from the ADA Scientific Sessions

We are landing in Chicago for the ADA Scientific Sessions and you can be sure that a veritable river of news about obesity will be flowing. Everything from basic science to innovative treatment and pragmatic approaches for clinical care and policy will be offered up by this meeting of the American Diabetes Association.

This promises to be a feast of insights that will take some time to consume.

Treatment Innovation

You can look forward to hearing a great deal of new clinical data on innovative new treatments. For one thing, we will get a detailed look at the data on CagriSema in a Sunday session at 8 am. Until now, we have had only glimpses of topline data through press releases from Novo Nordisk. The room will be packed.

Perhaps more interesting will be the Monday morning presentation on detailed data on bimagrumab and semaglutide from the BELIEVE study. This will be an opportunity to see what we should believe about an innovative approach to lose more adipose tissue and less muscle.

We will also be keen to see the detailed presentation on phase two results with MariTide – a monthly dual-acting new agent. The monthly dosing may offer real world benefits (we hope) with better, more persistent adherence. But it may have other virtues as well.

Other data on treatment innovation will certainly be interesting. They will range from very early insights on promising new mechanisms and molecules to the pivotal efficacy data for a small molecule oral drug – orforglipron – that will soon be going to FDA for approval. Yes, there will be a lot to absorb.

Clinical and Policy Insights

On Friday, we will be quite eager to hear what we can learn from a symposium on the ADA Standards of Care for Obesity and Overweight. To say the least, this is a fraught subject.

Another presentation that will get our attention is a late-breaking microsimulation study of the potential for better access to obesity treatment for reducing obesity prevalence and saving lives. We doubt it will be the final word on this subject. But it reflects a dramatic shift in the dialog about obesity and its treatment.

Click here and here for more on what to expect

Chicago River at Night, photograph by Daniel Schwen, licensed under CC BY-SA 4.0

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June 20, 2025