Posts Tagged ‘adipose tissue’

The Epigenetic Memory of Obesity Explains a Chronic Disease

November 19, 2024 — Fat cells don’t forget. That simple fact comes from new research published in Nature yesterday which explains a fundamental truth about obesity that eludes most people in their thinking about this condition. It is a chronic disease. Fat cells have an epigenetic memory for obesity they retain even when people lose a lot of weight. […]

Tracking Obesity into Cellular Mitochondria

February 15, 2024 — Science has come a long way from simplistic assumptions about fat tissue as some sort of fuel depot for the excess calories a person consumes. In fact, adipose tissue is a very active endocrine organ that regulates the use and storage of energy in ways that new research is explaining. At a cellular level, new […]

Adipose Tissue and Inflammation in Obesity

April 6, 2022 — The immune activity and inflammation linked to adipose tissue in obesity is getting a lot of attention. Part of this is due to the interaction of inflammation, obesity, and the risks of COVID-19. But even more interesting is the insight into obesity itself. The insight comes from new study in Science Translational Medicine. In short, […]

Form and Function of Fat in Obesity

February 5, 2022 — Energy storage? That is the obsolete view about the function of fat tissue that drives much of public health policy on obesity. Energy in, energy out. Eat less, move more. But in reality, fat tissue is an endocrine organ. It is highly active, complex, and essential for health. With exquisite detail, a new review paper […]

Does SARS-CoV-2 Target and Exploit Fat Tissue?

December 9, 2021 — More than a year ago in Obesity, Paul Ryan and Noel Caplice laid out a theoretical framework suggesting SARS-CoV-2 (the virus that causes COVID-19) might target and exploit fat tissue. They wrote: “Adipose tissue in individuals with obesity may act as a reservoir for more extensive viral spread, with increased shedding, immune activation, and cytokine […]

Potential Breakthrough in Understanding the Obesity Gene

August 21, 2015 — Among folks who really understand obesity, there’s a remarkable level of excitement about a potential breakthrough in understanding how the obesity gene works to cause obesity. This excitement springs from a paper published Wednesday in the New England Journal of Medicine. Melina Claussnitzer and colleagues from all over the world have documented how the FTO gene can […]