March 19, 2025 — Intriguing observations on the effect of retatrutide on cancer progression in mice appeared Friday in NPJ Metabolic Health and Disease. Retatrutide is the first triple agonist to progress in clinical development for obesity. Lilly said recently that they expect to release phase three clinical trial data for it later this year – earlier than previously […]
November 8, 2024 — Amid a steady stream of news from ObesityWeek, the CDC released new NHANES data this week documenting an ongoing rise in U.S. diabetes prevalence. Between 1999 and 2023, the age-adjusted prevalence of diabetes, diagnosed and undiagnosed, in adults rose from 9.7% to 14.3%. The total prevalence in adults between 2021 and 2023 was 15.8% – […]
October 31, 2024 — The eternal question about medical and surgical treatment for obesity in young persons is all about long-term outcomes. Will the net effect of highly effective treatment actually be to make their lives better? An impressive new analysis of ten-year outcomes for metabolic surgery in teens offers excellent insight. A Landmark Publication The Teen-LABS (Longitudinal Assessment […]
October 22, 2024 — Adolescence is hard. With respect to mental health, especially of late, the environment is especially harsh. Even harsher if an adolescent is living with obesity. So a recent study in JAMA Pediatrics showing teens with obesity are having fewer suicidal thoughts when they get a GLP-1 is welcome news. Authors Liya Kerem and Joshua Stokar […]
June 18, 2024 — In JAMA Pediatrics yesterday, a new RCT tells us that promising money to adolescents with severe obesity can prompt weight loss with meal replacements. Every teen in this study received free pre-portioned and calorie-controlled meals. But half of them received a $20 gift card for every 0.5% they lost from their body weight at the […]
June 13, 2024 — In the prevention of childhood and adolescent obesity, let us have our wishes and beliefs, but distinguish them from facts in evidence. Wishes are good things. They are the muses which impel us to action to work for a better future. Belief is a good thing. Our staunch belief that something can work gives us […]
November 30, 2023 — For the last two days, we have been both observing and participating in an NIH meeting on pharmacotherapy for obesity in children and youth that has been quite a pleasant surprise. Scientists, clinicians, parents, and young persons came together in a stimulating exchange of ideas. Perhaps the most notable dialogue focused on a desire to […]
January 22, 2023 — When the American Academy of Pediatrics released its clinical guideline for obesity, it put a spotlight on an odd kind of zero sum thinking. For people promoting this line of thought, the presumption seems to be that parents, advocates, and health professionals have to pick sides. Which is more worthy of our attention – eating […]
November 23, 2022 — Whether or not it’s by intention, when and if parents try to talk with their children about body weight, it comes across as finger wagging. In fact, research published earlier this year tells us many youth never want their parents to talk about their weight – especially not their fathers. Parents might want to offer […]
November 3, 2022 — Mind-blowing. That’s how pediatric obesity medicine expert Claudia Fox described the outcomes with semaglutide for teens with obesity at OW2022 yesterday. As she and a panel of experts in the field discussed this huge advance for teens with obesity, every seat and space to stand in the ballroom was taken. Daniel Weghuber presenting these results […]
