Posts Tagged ‘cardiometabolic health’

Survodutide and Tirzepatide Dash for a Splash with MASH

June 9, 2024 — At the EASL Congress 2024 in Milan, we witnessed quite a splash of new data on both survodutide and tirzepatide for MASH. Friday and Saturday gave us two headline presentations at the meeting and two publications in the New England Journal of Medicine. Lilly pronounced itself “very pleased” with the results of their SYNERGY-NASH study […]

Early Puberty, Obesity, and Endocrine Disruption

June 8, 2024 — Puberty is coming earlier for girls today, obesity in children is rising, and endocrine disruption seems to be playing a role in both of these phenomena. What’s more, exposure to endocrine disruptors follows a pattern of health disparities. This means that these environmental hazards may have the greatest effects on populations that already suffer disadvantages […]

From Weight Loss to Obesity to Cardiorenal Metabolic Health

March 22, 2024 — A profound shift in the understanding of medicines that help with excessive or abnormal fat is underway. A few years ago, everybody thought of these in only one frame of reference – weight loss drugs. But that is changing now. Discourse about them is moving from weight loss to obesity treatment and even further, to […]

Indication for Heart Health Marks a New Era in Obesity Treatment

March 9, 2024 — It’s official. FDA now says that semaglutide, in doses used to treat obesity, can prevent heart attacks, strokes, and deaths in persons with cardiovascular disease and overweight or obesity. This is nothing short of the dawn of a new era in obesity treatment. FDA Division Director John Sharretts said it clearly: “This patient population has […]

The Intersection of Heart, Kidney, and Metabolic Outcomes

October 13, 2023 — The handwriting is on the wall. Insurers can’t avoid covering obesity drugs forever, said a recent analysis from Bloomberg and they were right. What prompted that conclusion is the cascade of health outcome studies that make it unmistakeable. Treating obesity and and related metabolic diseases with advanced medicines like semaglutide has a dramatic effect on […]

Continuous Glucose Monitors for One and All?

February 12, 2022 — To each his own – because truly, one size will never fit all. We can find no better illustration for this than the idea that perfectly healthy people might want to wear a continuous glucose monitors. And yet we have a crop of new tech startups that want to put these glucose monitors on all […]

Intermittent Fasting: An RCT Says ‘Meh’

July 29, 2021 — Two years ago, intermittent fasting was a hot concept. The idea was that periods of fasting could have metabolic benefits and help with weight loss – better than simply restricting calories. Popular interest peaked in early 2020 and has since been declining. Now, a new RCT of intermittent fasting – small, but well controlled – […]

Boring Critical Details in a Flashy Intermittent Fast Study

October 12, 2020 — At first glance, it’s a fascinating study. An intermittent fast, gut microbiota, and an effect on the risk for heart disease – the title of this new study in JCEM pushes all the right buttons. But a look under the surface tells a different story. The primary outcome measures for this study were BMI and […]

An Enduring Link: COVID-19 and Cardiometabolic Health

September 18, 2020 — More experience with COVID-19 tells us that the relationship between COVID-19 and cardiometabolic health is more than a passing thing. It starts with the risk that obesity confers for worse outcomes with COVID-19. That was the first clue. But that’s not the end of it. Because people are learning that the effects of COVID-19 can […]

Metabolic Health, Sleepless Nights, and COVID-19

September 6, 2020 — Are we anxious? Judging by a huge leap in people filling prescriptions for anti-anxiety meds, the answer is clearly yes. Before COVID-19 was on our minds, those prescriptions were growing by a by a few percentage points, year over year. Once COVID-19 grabbed our attention, they jumped by 34 percent right away. Likewise, Rxs for […]