November 11, 2025 — Just skimming headlines about new medicines for obesity and surgery, comparisons seem to be a dominant theme. Some of these headlines tell us surgery is more cost-effective or delivers more durable results. Some of that is certainly true. But the deeper truth surfaces this week in JAMA and JAMA Network Open. Clinical experience and, increasingly, […]
June 5, 2025 — Regeneron announced tantalizing results for the combination of trevogrumab with semaglutide for losing fat while preserving muscle. With the combination of these two drugs, it appears that individuals might lose more fat mass and less muscle mass than with semaglutide alone. In short, the promise is for a better quality of weight loss, leaving people […]
August 16, 2023 — “If you thought that GLP-1 agonists would replace bariatric surgery you are wrong.” Neil Floch is not alone in saying this and new research adds to the reasons we suspect that he is right. In JAMA Surgery, Jessica Mok and colleagues tell us that one plus one equals three with the combination of bariatric surgery […]
