July 10, 2023 — In thoughtful reporting for Fortune, Rachel Shin explores the possibility for broader access to advanced obesity meds leading to lower prices. But it’s a bit of a chicken-and-egg puzzle because it might be more likely that lower prices will lead to broader access. Novopoly Shin calls it a Novopoly. Novo Nordisk invested billions of dollars […]
June 27, 2023 — The last of four big days at ADA2023 brought us astonishing results from three studies of a new obesity medicine, retatrutide. This is the first 3-in-1 metabolic receptor agonist to advance this far in clinical trials as a medicine for obesity or diabetes. Researchers presented phase 2 results for obesity, diabetes, and NAFLD – three […]
May 28, 2023 — “Money makes the world go around.” Joel Grey and Liza Minnelli explained this in Cabaret. But sorting it out in healthcare – and specifically in obesity care right now – is quite a challenge. A lot of money is in play and so the tension between greed, health, and obesity care is painfully obvious. The […]
December 31, 2022 — “It’s difficult to make predictions, especially about the future.” With this anonymous piece of wisdom in mind, it still makes sense to take a moment to look back at the trends that we hoped and expected to shape the year we complete today. So here’s a narrative report card on our 2022 trend predictions. You, […]
December 5, 2022 — Move over, Novo Nordisk and Eli Lilly. Amgen wants a piece of the action in obesity treatment. With some obvious pride of accomplishment, Amgen unveiled results from a phase 1 study of its dual action conjugate on Saturday. This new experimental drug, AMG 133, is a molecule that combines peptides to activate GLP-1 receptors (as […]
May 21, 2022 — Competition can be a great thing. In the past few weeks we’ve been hearing a lot about tirzepatide. The FDA just approved it for treating type 2 diabetes, hailing it as an important advance. Tirzepatide for obesity is a couple of years away, but the initial results of pivotal studies have been extremely impressive. So […]
May 14, 2022 — Yesterday, FDA approved tirzepatide for type 2 diabetes, calling it “an important advance.” The brand name will be Mounjaro. This is the same drug for which its maker, Eli Lilly and Company, announced remarkable results in a phase 3 obesity study barely two weeks ago. It is the first of its kind – a dual […]
February 9, 2022 — There’s a race heating up. It is a race to open the way for better obesity care and deliver better options. In this race, semaglutide (Wegovy™) has a head start. But a pack of other options are on the way. Yesterday in JAMA, results in a study of tirzepatide for treating type 2 diabetes tell […]
August 9, 2021 — Could it be that innovation and competition for better obesity care will overtake the health problem of obesity? We see several signs pointing to this. A decade ago, it was tough to get FDA to take obesity innovation seriously. So big pharma research was running from the challenge. Sanofi had invested heavily in developing rimonabant […]
February 22, 2021 — When NEJM recently published impressive results for a new obesity treatment, it caused quite a stir. Now it looks like semaglutide might have some serious competition coming right behind it. Late last week, Lilly announced results for two phase 3 studies of tirzepatide. These were both studies for type-2 diabetes. Effects on body weight were […]
