October 28, 2025 — A new study in JAMA suggests that AI can lead a fully automated diabetes prevention program and deliver outcomes that are just as good as programs with human coaches. Shall we view this as a threat? Or, more optimistically, as a tool to help with the challenge of delivering obesity care at scale? A Mobile […]
October 11, 2025 — In the International Journal of Obesity, obesity medicine physician and researcher Caroline Apovian offers a compelling case to favor a prediabetes indication for GLP-1s. She writes: “The approval of a GLP-1 for prediabetes will change the landscape for prevention of T2DM and its complications due to early detection. Currently, most individuals at risk of T2DM […]
April 29, 2025 — Is this a grand finale? Or a requiem? In The Lancet Diabetes & Endocrinology yesterday, a new 21-year analysis of outcomes from the Diabetes Prevention Program memorialized an epic study. Even after 21 years, the Diabetes Prevention Program yielded a 24% reduction in the cumulative risk of developing type 2 diabetes, along with detailed outcomes […]
March 21, 2025 — The new administration in Washington says it wants to Make America Healthy Again by bringing an intense focus on chronic disease. This is a concept we endorse without reservation. But talk is turning into balk when it comes down to following through on the scientific research essential for reducing the burden of chronic disease. A […]
August 21, 2024 — Yesterday, Eli Lilly and Company announced an impressive topline number from the results of a three-year study of tirzepatide in adults with obesity or overweight and prediabetes. That number was 94% prevention of progression from prediabetes to diabetes with tirzepatide. No, it was not 100%. But this is awfully close. Historical Context We will have to […]
March 14, 2023 — Recently, we have written much about the high cost of obesity medicines, limited coverage under health plans, and the need for change. This is a very real problem and glaciers melt faster (sad to say) than policy makers make progress on this. But absurd arguments about the cost of obesity care do not help. In […]
February 9, 2023 — Vitamin D is an illusory panacea. Popular fascination with this “sunshine vitamin” has drawn people to latch onto associations that it has with many conditions. But those associations, when tested, often turn out to be confounded. So does a new systematic review and meta-analysis of vitamin D in prediabetes tell a different story? Anastassios Pittas […]
September 24, 2022 — “There is more to obesity than meets the eye,” write James René Jolin and Fatima Cody Stanford in the Postgraduate Medical Journal. But too often, visible behaviors and appearances guide our responses to this disease. So we end up wondering why the result of earnest efforts to reduce it in both individuals and the population […]
February 1, 2022 — It is a familiar pattern, but no less disappointing because of that. A government commission issues a report and cries out for action. “Another health crisis challenges the U.S.: diabetes mellitus,” says the report issued yesterday by the National Clinical Care Commission. The report correctly identifies obesity as a key driver of rising deaths from […]
January 13, 2022 — The numbers are stark. More than 80 percent of Americans with diabetes are not meeting clinical targets to reduce heart disease risk. For people with both diabetes and obesity, more than 90 percent are bearing unnecessary risk. These numbers come from a new scientific statement in Circulation from the American Heart Association. On top of […]
