Posts Tagged ‘diversity’

Food Noise: All in the Ears of the Listener?

January 6, 2024 — We are hearing a cacophony lately – lots of noise about food noise. Part of what we hear is a celebration. Some people are finding blessed relief from it when they take advanced medicines for obesity like semaglutide or tirzepatide. Others see a threat in the relief that those people are finding. They deny that […]

Inflated Claims and Inadequate Testing for Rexulti

November 20, 2023 — FDA has a bone to pick with Otsuka, the company that sells Rexulti (brexpiprazole). The agency is taking issue with false advertising by the company for this drug used in schizophrenia and severe depression. To us, this problem of inflated efficacy claims is especially noteworthy because, for people with obesity who may need this drug, […]

Human Diversity, Identity, and Disease

November 19, 2023 — “I am.” These two words define so many struggles we face in public discourse today. People define their own identities in diverse ways and fiercely defend them. Disparage a person’s identity and you are attacking them. What follows is not gentle, rational, or easily calmed. Right now, we see how potent it is in public […]

Three Details Worth Knowing About the SELECT Study

November 12, 2023 — For some time to come, we will be learning more and more about the details and implications of the landmark SELECT study published yesterday in NEJM and presented at the American Heart Association Scientific Sessions in Philadelphia. A massive crowd packed the meeting hall yesterday for good reason. These results will change the practice of […]

Drug Studies, Labels, and Dosing Only for Lean Persons?

November 8, 2023 — Public health experts have long been accounting for it. People are living in larger bodies. Better than 40% of U.S. adults have a body weight in the range of obesity. But new reporting from JoNel Aleccia for the Associated Press tells us that pharma and the FDA are not yet accounting for this fact. It’s […]

A Troubling Gap: Body Size Diversity in Clinical Trials

July 7, 2023 — It’s a fact. People come in all shapes and sizes. FDA and pharmaceutical researchers know this. They know that body size and composition can have large effects on how a person responds to drugs. So why do we have such a troubling gap of body size diversity in clinical trials? In the AMA Journal of […]

Cheers for Banning Weight Discrimination in NYC

May 13, 2023 — Every now and then, it feels really good to score a win. On Thursday, the New York City Council passed a bill to add weight and height to the city’s list of characteristics protected from discrimination. Presently, that list includes race, gender, age, religion, and sexual orientation. If Mayor Eric Adams signs this bill into […]

The Oddness of Weight Bias in Eating Disorders

April 27, 2023 — “There’s a huge fatphobia problem in the eating disorder world,” says Shira Rosenbluth. She is a Licensed Clinical Social Worker, an eating disorder therapist, and has her own life experiences with eating disorders. Obesity and eating disorders can appear in the same patients and some research would suggest they frequently do. But for each of […]

The Failure to Test Drugs in People with Obesity

March 29, 2023 — Scientists and regulators at the FDA have identified a critical gap in new drug development and labeling. It is the failure to test new drugs in people with obesity. Where there are differences in clinical responses and safety, labeling – the instructions for safe use – should reflect those differences. But in many cases, they […]

Anecdotes and Studies of Lived Experiences with Obesity

March 19, 2023 — People want to be seen and heard. To feel like they matter. But in research and policy related to obesity, this fact was long neglected for many reasons. The principal reasons have much to do with stigma and the explicit dehumanization of people with this disease. With explicit efforts to overcome these issues, we see […]