Posts Tagged ‘drug dosing’

FDA Faces Questions About Drug Safety for People with Obesity

May 24, 2024 — At a hearing this week fo the U.S. House Committee on Energy and Commerce, Representative Robin Kelly asked the Director of the FDA Center for Drug Evaluation and Research, Patrizia Cavazzoni, what the agency is doing to ensure that drug labeling adequately protects the safety of people with obesity: “Patients with obesity are frequently excluded […]

ECO2024: Tailoring and Tapering Obesity Medicines

May 12, 2024 — A pair of studies with semaglutide at ECO2024 in Venice goes straight to the heart of some core questions about advanced obesity medicines. Does everyone need the full, maximum dose to get good results? Will everyone have to keep taking that full dose to keep obesity under control? The answer to both questions is no. […]

Will We Always Have to “Keep Taking” Obesity Medicines?

April 26, 2024 — Perhaps the most persistent fault that people find with new obesity medicines is the need to keep taking them forever. “Nobody is ready ” for that, says Business Insider. “Patients hate forever drugs,” says the New York Times. And they have a point. Obesity medicine doctors are quick to say “suck it up.” That’s just […]

Rethinking the Dosing of Obesity Medicines with AMG 133

February 6, 2024 — We learned recently that questions about the need for ongoing dosing with obesity medicines raise discomforting thoughts. After all, obesity is a chronic disease, so we can’t dispute the need for continued daily or weekly doses with obesity medicines. Or can we? Amgen seems to think we can. Monthly Dosing? Induction and Maintenance? With a […]

Fix the Blind Spot in Drug Trials Says Every Major Obesity Group

November 29, 2023 — It is time to translate words into action and fix the blind spot in drug trials and labeling for people with obesity. Every major obesity group in the U.S. issued this united call to action on Tuesday. This includes the ASMBS, Obesity Action Coalition, Obesity Medicine, Obesity Society, and STOP Obesity Alliance. It comes as […]

Drug Studies, Labels, and Dosing Only for Lean Persons?

November 8, 2023 — Public health experts have long been accounting for it. People are living in larger bodies. Better than 40% of U.S. adults have a body weight in the range of obesity. But new reporting from JoNel Aleccia for the Associated Press tells us that pharma and the FDA are not yet accounting for this fact. It’s […]

The Right Drug at the Wrong Dose in 4 Out of 10 Americans

October 23, 2023 — It’s a “deficit of information” we should correct, says FDA Commissioner Robert Califf. He is speaking about the gap in information about how to correctly dose drugs for people living with obesity. Karen Weintraub, reporting for USA Today, tells us this gap might mean that doctors are prescribing the right drug at the wrong dose […]