Posts Tagged ‘drug safety’

OW2024: A Blind Spot in Drug Labeling for Persons with Obesity

November 16, 2024 — Research presented at ObesityWeek 2024 shines a light on a blind spot in drug labeling for persons with obesity. No, we’re not talking about the latest buzzy drug for treating obesity. Rather, we are talking about a prime example of labeling for other drugs that people with obesity may need when they face a serious […]

Leaving Doctors in the Dark About Patients with Obesity

October 29, 2024 — In some ways, it is nothing new. The medical needs of people living with obesity have been dismissed seemingly forever. But at the same time it is shocking to learn of Merck – a highly respected pharmaceutical firm – leaving doctors in the dark by choice about how one of their drugs acts differently in […]

Fewer Suicidal Thoughts in Teens Getting a GLP-1

October 22, 2024 — Adolescence is hard. With respect to mental health, especially of late, the environment is especially harsh. Even harsher if an adolescent is living with obesity. So a recent study in JAMA Pediatrics showing teens with obesity are having fewer suicidal thoughts when they get a GLP-1 is welcome news. Authors Liya Kerem and Joshua Stokar […]

Losing Patience with Drug Labels Dismissing People with Obesity

September 9, 2024 — The American College of Clinical Pharmacology is meeting in Bethesda this week. On the opening day, ACCP convened a symposium to address critical questions about how drugs work in people with obesity. What can we – industry, FDA, and scientists – do better? Because all too often, drug labels to guide safe prescribing are effectively […]

Fix the Blind Spot in Drug Trials Says Every Major Obesity Group

November 29, 2023 — It is time to translate words into action and fix the blind spot in drug trials and labeling for people with obesity. Every major obesity group in the U.S. issued this united call to action on Tuesday. This includes the ASMBS, Obesity Action Coalition, Obesity Medicine, Obesity Society, and STOP Obesity Alliance. It comes as […]

Do Cancer Drugs Work Safely for People with Obesity? Maybe

November 18, 2023 — At a time when nearly half of the U.S. population is living with obesity, this should be an easy question to answer. Obesity clearly causes some forms of cancer and as the prevalence of obesity is rising, patterns of cancer prevalence are shifting, too. So, yes, we should be able to say with great confidence […]

Compounding, Biosimilars, Generics, and the Semaglutide Supply

October 30, 2023 — It leaves our heads spinning. Normal healthcare systems cannot keep up with the demand for a breakthrough in obesity treatment. The company, Novo Nordisk, which developed semaglutide for obesity treatment, has invested billions and now is reaping many billions of dollars in sales. But despite more than a decade of preparation, they can’t keep up. […]

OW2023: Testing Drugs in People Like Me

October 17, 2023 — “You’re either invisible, or the answer is to lose weight, even with mental health.” This is the sentiment that surfaced at OW2023 in research of lived experiences from people coping with both obesity and needing treatment for mental health concerns. It becomes acutely important as we learn that drug trials for conditions other than obesity […]

A Troubling Gap: Body Size Diversity in Clinical Trials

July 7, 2023 — It’s a fact. People come in all shapes and sizes. FDA and pharmaceutical researchers know this. They know that body size and composition can have large effects on how a person responds to drugs. So why do we have such a troubling gap of body size diversity in clinical trials? In the AMA Journal of […]

Sunshine, Lollipops, Rainbows, and GLP-1 Meds

April 30, 2023 — Recent advances in medicines for treating obesity are stirring up quite a conversation. The enthusiasm for them is hard to miss. Subway ads, tabloid headlines, and celebrities are putting these meds front and center. From all this enthusiasm for the new GLP-1 medicines, the impression might be something like sunshine, lollipops, and rainbows. No doubt, […]