Posts Tagged ‘health outcomes’

The launch of Foundayo, the first non-peptide GLP-1 tablet, last week marks more than a new medicine for obesity. More than the start of a new chapter for intense competition between Lilly and Novo Nordisk. GLP-1 tablets – Wegovy and Foundayo – seem likely to spark an important shift in discourse about obesity itself. For […]

The idea of junk food is an enduring concept that food policy advocates refresh endlessly to keep it in the public consciousness. Currently, the term of art is “ultra-processed.” Today, another study is commanding headlines to tell us these are bad foods. In this instance, the bad news is an association with 67% greater risk […]

Lilly announced new topline results from a phase three study for its next generation obesity and diabetes medicine yesterday. The drug, retatrutide, is a triple receptor agonist and it scored a dual win in this study. The primary aim of this study was to treat type 2 diabetes and show a good effect in lowering […]

New research published in The Lancet Diabetes & Endocrinology promises to shake up laissez faire attitudes about prediabetes. Elsa Vazquez Arreola and colleagues show, in post-hoc analyses of two landmark diabetes prevention trials, that reversing prediabetes can cut the risk of cardiovascular death or hospitalization by half in diverse populations. This finding, though it comes […]

Much of the world seems stuck on chasing ever higher numbers for weight loss. But clearly we need better targets for innovation in obesity and metabolic health. At the recent BIO Investment & Growth Summit, Immunis CEO Hans Keirstead came to tell us the answer lies in the health of our muscles. He has a […]

Are we on our way to progressing beyond weight loss as the primary end point for judging the value of new medicines in obesity? On this closing day of Obesity Care Week, topline results for a promising new obesity medicine – petrelentide – prompts us to reflect on this question. We suspect AI was making […]

Today, three of the leading voices for obesity care are releasing new guidance for obesity medicines in ongoing therapy. The Obesity Society, Obesity Medicine Association, and Obesity Action Coalition all came together in support of this important new guidance. Alongside its publication in the journal Obesity, Beverly Tchang and Donna Ryan offer a “humbling call […]

Obesity Care Week is well under way, so it’s time to take a minute to reflect upon how we frame obesity and how that matters for everyone’s health. It is instinctive to frame obesity as an issue of weight. But it is also utterly false. Though excess weight is the most prominent and visible symptom […]

This has been quite a year that we are closing out on this New Year’s Eve. As we start another new year, we will be leaving behind an ample collection of curses we suffered and blessings we enjoyed in 2025. No doubt, you have your list. So here is our own brief list of the […]

A new systematic review in Annals of Internal Medicine underscores something we’ve long said in obesity and nutrition science. The science of saturated fat is complex, and nuance is its first casualty when the headlines start spinning. A Risk-Stratified Analysis Steen and colleagues conducted a risk-stratified analysis of 17 randomized trials. It is the largest […]