Posts Tagged ‘heart failure’

Another Piece of the Heart Failure Puzzle for Semaglutide

August 24, 2024 — Novo Nordisk is creeping up on an indication for semaglutide in people with obesity and heart failure. Today in Lancet, we have another piece of the puzzle to suggest this drug might help. In a prespecified analysis from the SELECT study, researchers found that semaglutide reduced heart attacks, strokes, deaths, and problems with heart failure […]

Tirzepatide Cuts Adverse Heart Failure Outcomes by 38%

August 3, 2024 — One more chapter opened this week in the ongoing story of diseases that improve when healthcare providers effectively treat obesity. Lilly announced topline results from a study showing that tirzepatide cuts the rate of adverse heart failure outcomes in persons with obesity and heart failure by 38% when compared to placebo. The specific form of […]

Confirming the Benefit of Semaglutide in Heart Failure

April 8, 2024 — Obesity research never rests, it seems. Over the weekend, at the American College of Cardiology annual meeting and in the New England Journal of Medicine, we got a third confirmation of the benefit that semaglutide delivers to patients with obesity and heart failure. Specifically, this is about heart failure with preserved ejection fraction – HFpEF. […]

HFpEF: Actually Treating Obesity Makes the Difference

August 28, 2023 — On Friday, NEJM published impressive results in an RCT of semaglutide for treating patients who have obesity and heart failure with preserved ejection fraction (HFpEF). The treatment enabled these people to function better, feel better, and suffer half as many serious adverse events. These are important benefits for people with a very difficult condition. But […]

Impressive Semaglutide Outcomes in Obesity and Heart Failure

August 26, 2023 — Scientists who study semaglutide in obesity are producing a steady stream of impressive results. Yesterday in the New England Journal of Medicine, a randomized controlled trial in persons with obesity and heart failure with preserved ejection fraction demonstrated superior weight reduction, improvement in heart failure, better physical functioning, and a halving of serious adverse events. […]

HIIT Takes a Hit in an RCT for Certain Heart Patients

February 10, 2021 — High intensity interval training (HIIT) is hot right now. It mixes short periods of very intense exercise with less intense recovery. Even before the pandemic, interest in HIIT had grown dramatically. Then it spiked when pandemic lockdowns began. But a new RCT published yesterday in JAMA suggests that it might not be a panacea for […]

Prescribing and Delivering Better Nutrition

October 24, 2019 — Applying the science of health outcomes research to social determinants of health is bringing surprising insights. In fact, for chronic diseases like obesity, heart failure, and diabetes, delivering better nutrition might do more than merely prescribing medicine can. Also, it seems to seems to offer good value for money. Food Is Medicine? This catchphrase sometimes […]

Best Bet for a Healthy Holiday? Fresh Air

December 24, 2017 — It’s here. On this holiday, many people will stop everything as they gather with family for a festive time and seasonal foods. Maybe it’s a goose, maybe it’s eggnog. or maybe it’s Chinese food. Though a bit of mindfulness might help, the menu is probably out of your hands. So your best bet for seeking […]

Liraglutide and Heart Disease

November 10, 2015 — If you thought that the onslaught of new studies was done with the closing of ObesityWeek on Friday, think again. Now we have two important new studies of liraglutide and heart disease that were presented at the Annual Scientific Sessions of the American Heart Association (AHA) on Sunday and Monday. The study that’s hogging all the […]