Posts Tagged ‘innovation’

Food Shopping Now: Clicks, Lists, Frozen, and Local

September 9, 2020 — Eight years of change packed into one month. COVID-19 has changed food shopping. All of a sudden, everything about the ways we hunt and gather our meals is different. For one thing, we’re making fewer trips and more clicks. But we’re buying more and buying in new ways. Professor Anna Nagurney tells the New York […]

Hair Clippings to Measure Dietary Health

August 12, 2020 — Remember when haircuts were routine? Today, it seems, they’re a bit more special. The close contact they require makes it so. But new research also tells us that hair clippings from these close encounters can be valuable for dietary research. A team of researchers gathered up hair from barbershops and salons in diverse U.S. locations […]

Dietary Dark Matter: What Are We Eating?

July 23, 2020 — Do you know what you’re having for lunch? You might think so. But in fact, the food that we are consuming is so complex, that we only have a vague idea of what’s in it. Through a project called FooDB, scientists have cataloged more than 70,000 biologically active chemicals that may be present in our […]

The Tortured Pathway for a New NASH Treatment

June 30, 2020 — It’s tough getting good information these days. Good, factual information. Everybody wants to spin it. That’s undeniable in public policy. But it also seems to be true in drug development. Yesterday, the FDA definitively rejected an application from Intercept Pharmaceuticals for a new drug to treat NASH – nonalcoholic steatohepatitis. The company was shocked. Its […]

More Than One Trick in Obesity Innovation

June 19, 2020 — In pharmaceuticals, a one-trick pony is doomed to oblivion. Some companies have a big hit with a successful drug and then struggle to follow up with more innovation. So patents expire and sales dwindle. The company with one-trick innovation fades away. But with solid clinical trial results announced yesterday for two new drugs in obesity, […]

RCT: Metabolic Surgery Tops Best Medical Therapy

June 17, 2020 — A randomized controlled trial (RCT) in surgery is quite a challenge. For good reason, people are reluctant to sign up for a study in which they might randomly get surgery. Or not. Surgery is a big decision and leaving it to chance doesn’t sit well with most people. Yet an RCT is the very best […]

Quiet Progress: FDA OKs Setmelanotide Priority Review

May 18, 2020 — We call it stealth progress. Rhythm Pharmaceuticals last week gained approval from FDA for a priority review of setmelanotide for rare genetic forms of obesity in children. The indications are for obesity treatment in POMC and LEPR deficiency. Furthermore, the FDA has indicated it doesn’t plan to hold a public hearing on this drug This […]

Four Immediate Results of a Dead Stop in Healthcare

May 17, 2020 — We’re in the midst of a health crisis. And yet, oddly enough, healthcare has come to a halt in many ways. Dental offices are closed. People are staying away from their doctors. Emergency rooms are deadly quiet. Outside of the intense activity required to save the lives of people suffering severe encounters with COVID-19, healthcare […]

Pivotal Results for Semaglutide in Obesity

May 14, 2020 — Yesterday the process of a slow reveal began. Novo Nordisk released the first pivotal results in studies of semaglutide for obesity. This new drug, already available for diabetes, has potential to bring us closer to truly effective obesity treatment without surgery. This was merely a first glimpse – topline results from only one of four […]

Obesity Treatment for Teens: Liraglutide Coming Soon?

March 31, 2020 — While the world has been busy with COVID-19, quite a lot has been happening in obesity. Last week, JAMA Pediatrics published an important review of all the evidence-based options for treating obesity in adolescents. The bottom line? Those options are too few, but more are coming. Today, we got a good look at one of […]