Posts Tagged ‘medical innovation’

More News Points to Explosive Growth for GLP-1 Medicines

February 7, 2024 — Let’s be clear from the start. Hype about “weight loss” drugs is exquisitely unhelpful. This is because weight loss is only an acute effect of new medicines that act on GLP-1 receptors and related pathways that influence obesity. The real need for these medicines is to control a whole range of chronic health problems that […]

Rethinking the Dosing of Obesity Medicines with AMG 133

February 6, 2024 — We learned recently that questions about the need for ongoing dosing with obesity medicines raise discomforting thoughts. After all, obesity is a chronic disease, so we can’t dispute the need for continued daily or weekly doses with obesity medicines. Or can we? Amgen seems to think we can. Monthly Dosing? Induction and Maintenance? With a […]

Dreaming of Long-Term Success in Overcoming Obesity

December 29, 2023 — Right now, the public and policy makers are grappling with innovations in obesity that we already have. But scientists are peering over the horizon. They are dreaming – asking important questions about long-term success in overcoming obesity. Stat News describes this as a “quest to eradicate obesity” – a frame for this work that misses […]

2023: The Year Ozempic Took Over the World, for Better or Worse

December 26, 2023 — In the New Yorker, Dhruv Khullar calls 2023 “the year of Ozempic.” Then in Vox, Constance Grady puts it right up there with Barbie, calling this “the year of Ozempic bodies and Barbie Botox.” The New York Times puts it at the very top of five health lessons we learned in 2023. Most notably, Science […]

The Top 10 Most Read Posts of 2023 on ConscienHealth

December 21, 2023 — No two ways about it. This has been a big year of milestones in obesity and health. We and many others are still processing what we have witnessed in these past 12 months. But one way to gain perspective is to look at 2023 stats for the posts on ConscienHealth that you, a wise group […]

Pills and Pokes, Different People, Different Paths

December 17, 2023 — “Are you sure you want an Ozempic pill?” In the Atlantic, Yasmin Tayag poses this question. Back in June people were bubbling with enthusiasm at the prospect of an oral small molecule – orforglipron – that might work as well as injectable semaglutide. But Tayag offers caution that we share. One size, one approach, for […]

As Zepbound Launches, Will Access to Obesity Meds Improve?

December 6, 2023 — The Zepbound brand of tirzepatide is now available in U.S. pharmacies. This is a big deal because this launch marks the emergence of serious competition for advanced obesity medicines. Even (or perhaps especially) in healthcare, money indeed makes the world go around and one of the best checks on greed is competition. So as Zepbound […]

The Twisted Path to Better Obesity Medicines

August 18, 2023 — We are clearly on a path toward better obesity medicines, but reflecting on decades of work on this, clearly, the path is twisted. Describing this path, Gina Kolata writes: “Every so often a drug comes along that has the potential to change the world. Medical specialists say the latest to offer that possibility are the […]

ADA2023: An Amazing 3-in-1 Obesity Medicine

June 27, 2023 — The last of four big days at ADA2023 brought us astonishing results from three studies of a new obesity medicine, retatrutide. This is the first 3-in-1 metabolic receptor agonist to advance this far in clinical trials as a medicine for obesity or diabetes. Researchers presented phase 2 results for obesity, diabetes, and NAFLD – three […]

ADA2023: A Golden Age of Obesity Medicine?

June 26, 2023 — “We may be on the cusp of an era of astonishing innovation – the limits of which aren’t even clear yet,” writes David Wallace-Wells in the New York Times. Among other breakthroughs, he cites the transformation in care that semaglutide and tirzepatide are bringing for the most prevalent chronic disease in the world – obesity. […]