Posts Tagged ‘mendelian randomization’

Teasing Out Causality in Obesity and Depression

December 23, 2022 — Causality in the relationship between obesity and depression is mighty hard to discern in a rigorous way. For clinicians, it seems obvious that obesity creates a risk for depression. Likewise, the observation that depression in some patients can lead to obesity is easy to find. But understanding that causal relationship is a challenge. Mere association […]

Untangling the Metabolic Effects of Higher Adiposity

February 3, 2022 — We are pretty much done with the label of healthy obesity, because it is a perfect oxymoron. If a pattern of adiposity is healthy, then it’s not obesity. But newly published in eLife is a more thoughtful approach to this subject. This study seeks to untangle the metabolic effects of higher adiposity from other effects […]