April 26, 2025 — An enduring and versatile mainstay of therapy for type 2 diabetes, metformin never ceases to earn our respect. On Thursday in JAMA, researchers showed this humble drug delivers improvements in knee pain for persons with overweight or obesity and osteoarthritis. In this six-month study of 107 persons randomized to either placebo or up to 2,000 […]
March 27, 2024 — Much of the world is having a revelation. Stat News call is a revolution. So does Oprah. They are waking up to a very basic fact that we’ve been working with for decades now. Obesity is a chronic, treatable disease. Obesity medicine wasn’t born yesterday. But it has, at times, been lonely. Arthur Frank, a […]
June 12, 2023 — In many ways, COVID seems to be in the rear view mirror. Travel, meetings, and busyness have cranked up to a level that makes it seem like the pause we took for the pandemic is a distant memory. But not for folks who develop long COVID – which is about ten percent of people who […]
December 19, 2020 — Metformin is one of those drugs that is older than dirt and still quite useful. It has helpful effects in obesity. It’s a mainstay of drug therapy for type 2 diabetes. But metformin presents a bit of a puzzle in patients with diabetes who become infected with COVID-19. Some signs point to a benefit for […]
July 23, 2017 — Let’s face it. The evidence base for childhood obesity treatment is thin. We don’t need bad stats to muddy the waters even further. But a recent paper in Pediatrics does just that. The authors conducted a randomized controlled trial of metformin in 160 children with obesity. They enrolled equal numbers of male, female, prepubertal, and […]
August 13, 2014 — What’s with all this wonder drug talk about metformin? It’s already deemed one of the most essential drugs for diabetes treatment. Now a new study of mortality in people with type 2 diabetes is generating headlines about metformin helping people live longer — perhaps even people who don’t have diabetes. The investigators seem to be encouraging […]
