Posts Tagged ‘NAFLD’

Separate Hepatic Steatosis from Obesity? Not So Fast

November 11, 2020 — Nonalcoholic fatty liver disease. That’s the stigma-laden medical terminology for a condition also known as hepatic steatosis. This is a chronic disease that most often goes undetected, until it progresses to the inflamed state of hepatitis. But then it gets serious. The inflammation progresses to fibrosis. Liver failure or liver cancer can be the end […]

Semaglutide Hits a Milestone in NASH

May 7, 2020 — Nonalcoholic steatohepatitis – NASH – is a more severe form of fatty liver disease that can lead to cirrhosis and liver cancer. Like other complications of obesity, people can develop NASH even if their BMI does not fall into the range of obesity. Just like obesity, the prevalence of NASH is growing and the treatment […]

A Steep Price to Pay for Untreated NASH

January 11, 2020 — A new study in the January issue of Diabetes Care makes one thing very clear. We pay a steep price for untreated NASH – nonalcoholic steatohepatitis. This is a disease that starts with fat tissue building up in the liver. Then inflammation develops. After that, it can progress to liver damage and failure, ultimately requiring […]

Obesity and Diabetes Bringing More Liver Disease

August 19, 2019 — The nature of liver disease is shifting in the U.S. Over the last three decades, hepatitis C has dropped by nearly half. But over that same time, we’ve seen more liver disease due to obesity and diabetes. In fact, NAFLD (non-alcoholic fatty liver disease) has grown in almost perfect synchrony with obesity and type 2 […]

Intercept Presents Encouraging NASH Results

April 12, 2019 — It’s been a long road for Intercept Pharmaceuticals to develop an important advance for treating NASH (non-alcoholic steatohepatitis). Five years ago this little startup company shocked the world when a monitoring board stopped a placebo-controlled study because their drug (obeticholic acid or OCA) had worked so well. A final round of 64 liver biopsies were […]

Cutting Sugar Clears Up Liver Disease in Children?

January 25, 2019 — JAMA grabbed some headlines this week on a popular subject – cutting sugar consumption for kids. Fatty liver disease is a serious problem and the headlines point to a simple solution. “To fight fatty liver, avoid sugary foods and drinks,” said the New York Times. How did researchers prove that? All it took was a randomized […]

NASH: The Invisible Complication of Untreated Obesity

November 28, 2017 — When most people think about obesity, the only complication they think of is type 2 diabetes. Quite a few people (but not a majority) think of heart disease. But few people think about liver disease. Unfortunately, Nonalcoholic steatohepatitis (NASH) can be one of the most serious complications a person with obesity will face. NASH is […]