November 5, 2025 — On the opening day of ObesityWeek yesterday, we got quite a treat in a passionate debate of the Lancet Commission report on clinical obesity. Four of our favorite people – Sue Yanovski, Bob Kushner, Fatima Cody Stanford, and Donna Ryan – participated and made it memorable. We walked away with a clear understanding that many […]
October 11, 2025 — In the International Journal of Obesity, obesity medicine physician and researcher Caroline Apovian offers a compelling case to favor a prediabetes indication for GLP-1s. She writes: “The approval of a GLP-1 for prediabetes will change the landscape for prevention of T2DM and its complications due to early detection. Currently, most individuals at risk of T2DM […]
September 3, 2025 — The magical Mirror of Erised can drive people mad by showing them their deepest desires. Judging by the flood of papers in recent days, it seems that one such desire is to find consensus for a clinical definition of obesity. In the past week alone, three such publications have crossed our screens. In the past […]
August 25, 2025 — The evidence keeps building. Broadly, it is telling us that treating obesity is about much more than simply losing weight. It is about gaining health by managing the chronic disease of obesity and controlling it over time. Specifically this week, we have another piece of evidence to suggest that obesity treatment prevents cancer. In JAMA […]
June 2, 2025 — This is stunningly positive news. While many of us are debating the nuances and evidence for lifestyle therapy in obesity, a clever group of cancer researchers have gone out and proven its value for extending life in people with colon cancer. A well-controlled clinical trial of personal coaching for exercise showed that it reduced cancer […]
May 10, 2025 — As we are on the way to the European Congress on Obesity in Málaga, Spain, one thing stands out. The science presented at this conference will make it plain that obesity is about much more than just excess weight and weight loss.We are looking forward to an array of presentations that deal with the effects […]
May 1, 2025 — Late yesterday, the New England Journal of Medicine published interim results from a study that points to another breakthrough for semaglutide – this time for a MASH indication. The analysis includes 800 patients with MASH with an average BMI of 34.5. Only 22 patients in this trial had a BMI that indicated leanness. Nearly two […]
January 4, 2025 — The ongoing debate about the clinical definition of obesity is soon to get more intense. But already, it tells us pretty clearly that obesity is defined by more than excess weight. New research in Nature Medicine comes at this subject from an entirely different direction. Using proteomics, Lasse Maretty and colleagues find that the effects […]
December 26, 2024 — This has been quite a year. We’ve seen endless death and destruction in Ukraine and the Middle East. People expressed discontent with the status quo in elections all over the world. But most notably for our readers – more than 100,000 of you this year – the progress on obesity and health has been nothing […]
December 21, 2024 — For patients with obesity and sleep apnea, FDA approved a first yesterday. Tirzepatide became the first ever drug with an FDA-approved indication for treating sleep apnea in persons with obesity. The data for this data appeared in the New England Journal of Medicine earlier this year. Atul Malhotra and colleagues found: “In two trials, the […]
