December 1, 2025 — Soybean oil is the most common cooking oil in the American food supply. By far. If you are consuming a lot of ultra-processed foods, you are consuming a lot of soybean oil. Now, the University of California at Riverside says that a new study links soybean oil to obesity. Specifically, scientists at the university have […]
November 28, 2025 — A new research letter in JAMA tells us that more new mothers are using GLP-1s for weight management. The rise of use in this context is dramatic – roughly 500% between 2022 and 2024. Note that these data come from Denmark. There, we estimate the per capita use of GLP-1s for obesity is somewhat less […]
November 26, 2025 — It seems like some good news is overdue for Novo Nordisk. So the topline report of a phase two study with amycretin that looks like a plausible win is especially welcome. The results at hand come from a 36-week placebo controlled study with a wide range of oral and injection doses in persons with type […]
November 21, 2025 — The sprint to the finish for orforglipron is picking up pace with a pivotal trial in obesity and diabetes published yesterday in The Lancet. Things are looking good for this relatively simple GLP-1 agonist in a tablet. The presentation of these results from ATTAIN-2 were a highlight of ObesityWeek earlier this month, but having this […]
November 15, 2025 — Anyone who thought this would be a passing thing was way off the mark. As prices of GLP-1 medicines are falling, their use is rising. As Stat News notes, we now have more people using these medicines than the entire population of Texas. This rising trend occurs against a background of costs that are still […]
November 14, 2025 — Tired, poor, huddled masses, yearning to breathe free? Those words are “inoperative” now in the U.S. State Department. New guidance from the top suggests America doesn’t want people with obesity getting a visa enter the country. Secretary of State Marco Rubio has issued a directive to U.S. embassy and consular officials all over the world, […]
November 13, 2025 — It would be odd to think that medical schools would stigmatize the most prevalent chronic disease that medical students will encounter. But stigmatizing obesity in medical schools is all too common, even today. Kofi Essel and colleagues published a study of the obesity bias observed by third year medical students at George Washington University School […]
November 12, 2025 — This is a perilous and exciting time for investing in obesity innovation as the market for treating this disease advances dramatically. On the side of excitement, we note that the David Wainer in the Wall Street Journal predicts that “obesity drugs are about to go mass market.” Perilous for Novo On the side of peril, […]
November 11, 2025 — Just skimming headlines about new medicines for obesity and surgery, comparisons seem to be a dominant theme. Some of these headlines tell us surgery is more cost-effective or delivers more durable results. Some of that is certainly true. But the deeper truth surfaces this week in JAMA and JAMA Network Open. Clinical experience and, increasingly, […]
November 10, 2025 — At a press event last week, announcing a deal to make obesity medicines more affordable, CMS Administrator Mehmet Oz told us “Americans will lose 135 billion pounds by the midterms” because of this. Comedian Stephen Colbert pointed out a problem with the numbers. They imply that every single American will be losing 393 pounds. It […]
