Posts Tagged ‘Prader-Willi syndrome’

Glimmering Edifice

A Glimmer of Hope for Beloranib

January 23, 2016 — The folks at Zafgen released a glimmer of hope for beloranib this week. On Wednesday, Zafgen announced that this investigational new drug met its two primary efficacy endpoints in the pivotal clinical trial for treating Prader-Willi syndrome (PWS). In December, that trial was halted after a second patient suffered a fatal blood clot in the […]

Uncertain

Patient Death Means Uncertain Future for Zafgen Obesity Drug

October 24, 2015 — Zafgen, a small biotech company “dedicated to the treatment of obesity,” is learning about the risks of their strategy of focusing on drug development for severe obesity. We’ve commented before that their focus is impressive and now it’s being tested. The pivotal randomized controlled trial (RCT) of the lead Zafgen obesity drug, beloranib, was halted after […]