Posts Tagged ‘randomized controlled trials’

Adding Stigma to Obesity and Heart Disease

January 24, 2023 — These are three problems that often travel together. But each one by itself is a problem – stigma, obesity, and heart disease. Now, a new study from the University of Connecticut gives us some of the best empiric evidence yet for the distinct harm that weight stigma adds to obesity and heart disease. Randomized and […]

FTC Asks for RCTs, Not Vague Health Claims

January 7, 2023 — Who knew that FTC could be a source of support for scientific rigor? Well, late in December the agency issued new guidance – its first in 25 years – clarifying the standards it requires for businesses making health claims about their products. In this new guidance, FTC makes a clear call for RCTs (randomized controlled […]

Protein: Magic Ingredient for Intermittent Fasting?

January 6, 2023 — Intermittent fasting has some enthusiastic fans. While some studies have shown impressive benefits, others have found little benefit. On top of that, virtually all of the research on this type of dietary intervention has been of a short duration. Compliance with intermittent fasting can be a challenge over time. So the fan base will surely […]

Big Claims, Vexing Flaws of an Intermittent Fasting Study

December 21, 2022 — Clinical research is hard to do right – especially if the goal is to discover the true answer to a scientific question. Because scientists are human, they bring passion to their work. But they have to set aside those passions in designing and conducting research so that their research will hold up to scrutiny. Along […]

How Helpful Is Early Time-Restricted Eating?

August 9, 2022 — We are not done with the notion of time-restricted eating. Two new studies tell us that it might be helpful. One is specifically about weight loss with early time restricted eating. The other is a simple test of the metabolic effects of limiting the window for eating to ten hours in the day – all […]

Ten Ways Bias Creeps into Randomized Studies

July 30, 2021 — Improving health through nutrition is important. Relieving the considerable suffering that obesity causes is likewise important. But both of these tasks are difficult. That’s because clear evidence for cause and effect is hard to find in nutrition and obesity. Randomized studies are hard. Observational studies are more common, but they are subject to bias from […]

High-Dose Vitamin D for COVID-19 Flunks Again

February 18, 2021 — The COVID-19 pandemic has taught us many things, big and small. One of the unexpected insights is the fervor that exists for vitamin D. It’s a potent vitamin with many effects. Too little of it in a person’s body can cause any number of problems. Too much can be a serious problem as well. It […]

HIIT Takes a Hit in an RCT for Certain Heart Patients

February 10, 2021 — High intensity interval training (HIIT) is hot right now. It mixes short periods of very intense exercise with less intense recovery. Even before the pandemic, interest in HIIT had grown dramatically. Then it spiked when pandemic lockdowns began. But a new RCT published yesterday in JAMA suggests that it might not be a panacea for […]

Compelling Outcomes in Metabolic Surgery Over Time

January 23, 2021 — Time ticks by. Millions of people live with obesity and its complications. Meanwhile, a steady stream of new studies offers compelling data on metabolic surgery outcomes. This week, it was a ten-year study in Lancet. This study provides the first data for an RCT of surgery versus medical therapy for type 2 diabetes beyond five […]

Will Opening Gyms Spread COVID-19? An RCT

June 26, 2020 — People are dying to get back to normal right now. Or at least, judging by news reports, some are certainly willing to take risks. Gyms are a particular sore spot. Michigan Governor Gretchen Whitmer has been in court to prevent gyms from opening and spreading COVID-19 in her state. Other states are opening their gyms. […]