Posts Tagged ‘research’

Dietary Dark Matter: What Are We Eating?

July 23, 2020 — Do you know what you’re having for lunch? You might think so. But in fact, the food that we are consuming is so complex, that we only have a vague idea of what’s in it. Through a project called FooDB, scientists have cataloged more than 70,000 biologically active chemicals that may be present in our […]

Is Reviewer 2 the Source of All Our Woes?

July 7, 2020 — Welcome to the world of peer review. This is the vital tool for bringing you science that you can trust. Legions of earnest experts look over research papers for strengths and weaknesses and overall merit before they appears in press. But urban legend holds that there’s a villain lurking in the process – Reviewer 2. […]

Calories, Carbs, Quality, and Obesity

July 6, 2020 — For decades now, we’ve been debating the role of macronutrients in weight gain. But that fierce debate has yielded precious little consensus. Low-fat dietary guidance ruled the land for decades. Right now, low-carb diets seem to have the upper hand. However, in a new webinar, Kevin Hall suggests that neither calories, carbs, nor fat tell […]

Proving an Important Point with a Lousy Study

June 24, 2020 — “In your heart, you know he’s right.” That political tagline was a loser in 1964 and it ranks as one of ten worst of all time. But it’s even worse if such thinking is applied to science. A study seems to prove an important point at a critical moment. So it’s rushed into publication. Then […]

More Than One Trick in Obesity Innovation

June 19, 2020 — In pharmaceuticals, a one-trick pony is doomed to oblivion. Some companies have a big hit with a successful drug and then struggle to follow up with more innovation. So patents expire and sales dwindle. The company with one-trick innovation fades away. But with solid clinical trial results announced yesterday for two new drugs in obesity, […]

Obesity Treatment for Teens: Liraglutide Coming Soon?

March 31, 2020 — While the world has been busy with COVID-19, quite a lot has been happening in obesity. Last week, JAMA Pediatrics published an important review of all the evidence-based options for treating obesity in adolescents. The bottom line? Those options are too few, but more are coming. Today, we got a good look at one of […]

Rising Conflict: Reason and Emotion in Health Policy

March 25, 2020 — We’re witnessing some intense interchanges on health policy right now. Reason and emotion are in vivid conflict. Jolting comments collide with disturbing facts. The new coronavirus “will disappear like a miracle,” says one policymaker. In addition, we hear promises of “packed churches all over our country” in just a couple of weeks. But then, a […]

Embracing Failure in Behavioral Obesity Care

March 13, 2020 — Through the last four decades of relentlessly rising obesity, we’ve had two clinical strategies in play. The first approach – arguably dominant – has been to overlook obesity and merely treat the complications as they appear. The other is intensive behavioral treatment. But clearly, neither of these have been adequate. The burden of chronic diseases […]

A Bright Red Line Between Research and Proving a Point

March 8, 2020 — We occupy an interesting dwelling place at the intersection of advocacy and science. By doing so, we have the gift of constant reminders to pay attention to a bright red line. That line marks the very important distinction between research and proving a point. Too often in obesity and nutrition, we have lost sight of […]

The Genes to Stay Lean in a Fat World

February 27, 2020 — We are swimming in a sea of implicit weight bias. At its most basic, the bias is this: obesity is a behavioral problem. When we tell people, no, it’s a problem of physiology, most often they can’t accept it. Tell them it’s highly heritable and they often spit back at us. “Genes are not destiny!” […]