April 18, 2025 — The news in obesity research these days is so full of headlines about a multitude of new medicines in development that it is easy to lose count. All too often, these are early stage or even pre-clinical notions of a potential treatment. So yesterday, it was good news indeed to hear that a once-daily oral […]
December 7, 2024 — The concept of turning food into medicine mildly repels us. But telling us chocolate is medicine simply goes over the line. Yet here comes a study in the BMJ, spinning off headlines about dark chocolate as a “bittersweet remedy for diabetes risk.” Milk chocolate? Nope. In fact, the authors of this observational study say milk […]
November 14, 2024 — In the New England Journal of Medicine yesterday, detailed results of a three-year study showed that tirzepatide was 99% effective in preventing diabetes in people with prediabetes and obesity. This was a placebo-controlled trial. Every person in the study, whether they received tirzepatide or not, received regular lifestyle counseling. Compared to the control group getting […]
October 10, 2024 — After a recent cascade of diverse studies yielding seemingly different answers about time-restricted eating, FNCE this week provided an excellent opportunity to gain perspective from researchers who are serious about this subject. Krista Varady, Shuhao Lin, and Vicky Pavlou brought a much needed focus on the science behind this pop nutrition phenomenon. A Helpful Alternative […]
August 30, 2024 — Scientists have a pretty good handle on how to predict a person’s risk of diabetes and how to diagnose it. The gold standard is a glucose tolerance test. How does your body handle glucose? But diabetes is just one dimension of dietary disease risk and nutrition scientists are hungry for a better way to predict […]
August 28, 2024 — Type 2 diabetes prevalence is up and the Lancet Regional Health has a simple way to reduce it. Daniel Windred and colleagues write: “Advising people to turn off their lights at night, or use lights that reduce the circadian impact (dim and “warm” light), is a simple, cost-effective, and easily-implementable recommendation that may promote cardiometabolic […]
August 22, 2024 — From time to time, nutritional epidemiologists take themselves entirely too seriously. This week is one of those times. Health reporting is full of warnings that your lunch sandwich might give you type 2 diabetes. The senior author of the paper in Lancet Diabetes and Endocrinology causing this stir, Professor Nita Forouhi, expresses no caution about […]
August 21, 2024 — Yesterday, Eli Lilly and Company announced an impressive topline number from the results of a three-year study of tirzepatide in adults with obesity or overweight and prediabetes. That number was 94% prevention of progression from prediabetes to diabetes with tirzepatide. No, it was not 100%. But this is awfully close. Historical Context We will have to […]
August 10, 2024 — This is an impressive sales push. A diet of soups and shakes offers a brilliant path to weight loss, changing the lives of people with obesity and diabetes. So says the director of the NHS Type 2 Diabetes Path to Remission program, Clare Hambling: “It’s brilliant that these findings show a large number of those […]
August 1, 2024 — On the theme of “Is there anything GLP-1s can’t do?” a new randomized controlled trial is coming at us from the Alzheimer’s Association International Conference. It showed promising signs that a GLP-1, liraglutide, might slow the progression of Alzheimer’s disease. Liraglutide is used under the brand name Victoza to treat type 2 diabetes. At higher […]
