September 2, 2024 — It’s true. We have been getting some pretty good news about GLP-1s lately. In persons with prediabetes and obesity, tirzepatide was 94% effective at preventing the development of diabetes. In the SELECT study, semaglutide for obesity might have cut COVID fatalities by a third. So a little exuberance about the potential of GLP-1 medicines is […]
August 27, 2024 — How big might the semaglutide budget bomb be? The authors of a new brief report in Annals of Internal Medicine today are making a point. How threatening can we make this sound? Right up front in their title, they label their estimates as the “maximum costs of expanded Medicare coverage of semaglutide for cardiovascular risk […]
August 9, 2024 — This week has given us a study in contrasts. The leading makers of obesity medicines, Lilly and Novo Nordisk, posted quarterly reports and received sharply different responses. When Novo Nordisk released their report on Wednesday, the market value of the stock plunged by eight percent. The next day, Lilly reported results and saw its market […]
August 5, 2024 — Should we celebrate the news that, in FDA drug shortage listings, all forms of tirzepatide (Mounjaro and Zepbound) are listed as “available”? Is this a sign that we are on our way to the nightmarishly short supply of GLP1s will soon be behind us? Forgive us for being skeptical, but we’re not quite ready to […]
June 12, 2024 — Senator Bernie Sanders doesn’t want to let this go. Novo Nordisk isn’t eager to cut its thousand-dollar list price for Ozempic. Nor is it eager to face a grilling about this in the Senate. So yesterday, Sanders announced that the Senate Health, Education, Labor, and Pensions committee will vote next Tuesday on a subpoena for […]
April 30, 2024 — Last week, the U.S. Senate launched an investigation into the high price of semaglutide, sold as Ozempic and Wegovy by Novo Nordisk. Yes, pressure on GLP-1 pricing is building and you can be confident there’s more to come. Senator Bernie Sanders chairs the Senate Committee on Health, Education, Labor, and Pensions, which is undertaking this […]
March 28, 2024 — A new economic analysis in JAMA Network Open brings unsurprising news: manufacturing costs for GLP-1 agonists are a tiny fraction of the price for these important medicines. This is always the case for innovative prescription drugs that must recover billions of dollars of development costs in order to be profitable. The response from policy makers […]
March 22, 2024 — This is a striking change. Until now, the steadfast refusal of CMS to allow coverage of any obesity medicine by Medicare has been unwavering. Then two weeks ago, FDA granted a new indication for semaglutide for persons with both heart disease and obesity to prevent heart attacks, strokes, and deaths. Now CMS says it’s A-OK […]
March 18, 2024 — Hear that rumble? Nope, it not the latest SpaceX launch. It is the roar of growing demand for obesity care in the U.S. Two pieces of news in the last week remind us of how steep the upward line of growth in obesity treatment is right now. To help it scale up their reach to […]
March 9, 2024 — It’s official. FDA now says that semaglutide, in doses used to treat obesity, can prevent heart attacks, strokes, and deaths in persons with cardiovascular disease and overweight or obesity. This is nothing short of the dawn of a new era in obesity treatment. FDA Division Director John Sharretts said it clearly: “This patient population has […]
