Posts Tagged ‘Zepbound’

It would be hard to find a sharper contrast than the one displayed yesterday in the report of fourth quarter 2025 business results for Eli Lilly and Novo Nordisk. Lilly is enjoying the best of times. Novo is suffering the worst. “Eli Lilly’s GLP-1 growth is only getting started,” says CNBC, “as Novo Nordisk braces […]

Usually, when new medicines have been on the market for a time, warnings tend to accumulate in the prescription labeling. So it is a bit unusual to see the FDA move to remove a warning. But recently, that’s exactly what happened with semaglutide and tirzepatide. FDA is making a course correction on warnings about suicidal […]

Yesterday’s news from the business of developing and selling obesity medicines reveals a lot. Lilly told us tirzepatide is now the biggest-selling drug of any kind in the world and Novo Nordisk started a highly unusual bidding war with Pfizer for Metsera. Metsera is a biotech startup focused on obesity medicines. Booming Tirzepatide Lilly announced […]

When the new administration announced in April that it would not be implementing expanded access to obesity medicines in Medicare, they suggested this would not be the final word. Yesterday, we got a hint of what might come. Paige Winfield Cunningham reported in the Washington Post that CMS has drafted a plan to allow Medicare […]

The word of the day in obesity is volatility. Minutes ago in Denmark, Novo Nordisk announced their first quarter business results and revealed a 13% drop in obesity drug sales, a reduction in their sales forecast, and yet the response in European stock markets was that the stock rose in value. In fact, it rose […]

Rather quietly this week, Eli Lilly and Company announced that it had withdrawn an application to FDA for an indication to use tirzepatide (Zepbound) in treating heart failure – specifically for HFpEF. This news came up in a briefing for investors, with Lilly’s Chief Scientific Officer, Dan Skovronsky, saying: “Following discussions with the FDA, we’ve […]

The last legitimate path for GLP-1 compounding closes on May 22 and consumer protection advocates are worried about rabbit holes opening up to exploit the desperation of some patients. Yesterday, the National Consumer League (NCL) released survey results to suggest a great deal of confusion and misinformation about off-brand versions of GLP-1 medicines. Perhaps more […]

A new analysis in JAMA Health Forum yesterday shines a harsh light on pricing for new obesity medicines. In a rigorous econometric analysis, researchers found that new and highly effective medicines for obesity – Wegovy (semaglutide) and Zepbound (tirzepatide) – are both overpriced. They also found that the price and value of Wegovy was out […]

Prices are moving quickly for people seeking obesity treatment with semaglutide and tirzepatide. Last week, Lilly offered another price cut for Zepbound. At the time, we noted inaction from Novo Nordisk on this front. But it barely took a week for this formerly unchallenged market leader to step up and respond with a huge price […]

Just days after an FDA ruling that will force most compounders out of the market for obesity medicines, Eli Lilly announced yet another carefully calibrated price cut for its Zepbound brand of tirzepatide. These are direct-to-consumer prices for the product packaged in vials. Specifically, Lilly offered up two new, higher dose vials at a reduced […]